Category Archives: Heart health

Good News Monday: How to Live Longer

[from the New York Times]

An illustration of a person standing in a yoga pose with leaves emanating from different parts of the body; on either side of the person is an infinity loop with various vignettes; the vignettes are a couple on a couch, a person sleeping, a bowl of fruit and a person running.
Credit…Cristina Spanò

By Dana G. Smith

Humans have searched for the secret to immortality for thousands of years. For some people today, that quest includes things like sleeping in a hyperbaric chamber, experimenting with cryotherapy or blasting oneself with infrared light.

Most aging experts are skeptical that these actions will meaningfully extend the upper limits of the human life span. What they do believe is that by practicing a few simple behaviors, many people can live healthier for longer, reaching 80, 90 and even 100 in good physical and mental shape. The interventions just aren’t as exotic as transfusing yourself with a young person’s blood.

“People are looking for the magic pill,” said Dr. Luigi Ferrucci, the scientific director of the National Institute on Aging, “and the magic pill is already here.”

Below are seven tips from geriatricians on how to add more good years to your life.

The number one thing experts recommended was to keep your body active. That’s because study after study has shown that exercise reduces the risk of premature death.

Physical activity keeps the heart and circulatory system healthy and provides protection against numerous chronic diseases that affect the body and mind. It also strengthens muscles, which can reduce older people’s risk of falls.

“If we spend some of our adult years building up our muscle mass, our strength, our balance, our cardiovascular endurance, then as the body ages, you’re starting from a stronger place for whatever is to come,” said Dr. Anna Chang, a professor of medicine specializing in geriatrics at the University of California, San Francisco.

The best exercise is any activity you enjoy doing and will stick with. You don’t have to do a lot, either — the American Heart Association recommends 150 minutes of moderate-intensity exercise per week, meaning just walking a little more than 20 minutes a day is beneficial.

The experts didn’t recommend one specific diet over another, but they generally advised eating in moderation and aiming for more fruits and vegetables and fewer processed foods. The Mediterranean diet — which prioritizes fresh produce in addition to whole grains, legumes, nuts, fish and olive oil — is a good model for healthy eating, and it’s been shown to lower the risk of heart disease, cancer, diabetes and dementia.

Some experts say that maintaining a healthy weight is important for longevity, but to Dr. John Rowe, a professor of health policy and aging at Columbia University, that’s less of a concern, especially as people enter old age. “I was always more worried about my patients who lost weight than my patients who gained weight,” Dr. Rowe said.

Sleep is sometimes overlooked, but it plays a major role in healthy aging. Research has found that the amount of sleep a person averages each night is correlated with their risk of death from any cause, and that consistently getting good quality sleep can add several years to a person’s life. Sleep appears to be especially important for brain health: A 2021 study found that people who slept less than five hours a night had double the risk of developing dementia.

“As people get older, they need more sleep rather than less,” said Dr. Alison Moore, a professor of medicine and the chief of geriatrics, gerontology and palliative care at the University of California, San Diego. Seven to nine hours is generally recommended, she added.

This goes without saying, but smoking cigarettes raises your risk for all kinds of deadly diseases. “There is no dose of cigarette smoke that is good for you,” Dr. Rowe said.

We’re starting to understand how bad excessive alcohol use is, too. More than one drink per day for women and two for men — and possibly even less than that — raises the risk for heart disease and atrial fibrillation, liver disease, and seven types of cancer.

Nearly half of American adults have hypertension, 40 percent have high cholesterol and more than one-third have pre-diabetes. All the healthy behaviors mentioned above will help manage these conditions and prevent them from developing into even more serious diseases, but sometimes lifestyle interventions aren’t enough. That’s why experts say it’s critical to follow your doctor’s advice to keep things under control.

“It’s not fun to take the medications; it’s not fun to check your blood pressure and check your blood sugar,” Dr. Chang said. “But when we optimize all those things in a whole package, they also help us live longer, healthier, better lives.”

Psychological health often takes a back seat to physical health, but Dr. Chang said it’s just as important. “Isolation and loneliness is as big a detriment to our health as smoking,” she said, adding that it puts us “at a higher risk of dementia, heart disease, stroke.”

Relationships are key to not only living healthier, but also happier. According to the Harvard Study of Adult Development, strong relationships are the biggest predictor of well-being.

Dr. Rowe tells the medical students he teaches that one of the best indicators of how well an elderly patient will be faring in six months is to ask him “how many friends or family he’s seen in the last week.”

Even thinking positively can help you live longer. Several studies have found that optimism is associated with a lower risk of heart disease, and people who score highly on tests of optimism live 5 to 15 percent longer than people who are more pessimistic. That may be because optimists tend to have healthier habits and lower rates of some chronic diseases, but even when accounting for those factors, the research shows that people who think positively still live longer.

If you had to pick one healthy practice for longevity, “do some version of physical activity,” Dr. Moore said. “If you can’t do that, then focus on being positive.”

Good News Monday: Bonus Round

I don’t know about you, but I could use a little extra good news these days. This story comes from Georgia, so it may be a little biased. (Georgia produces one-third of the pecan harvest in the US: nearly 88 million pounds of pecans from over six thousand pecan trees.) Still food for thought.

Image by Lisa Redfern from Pixabay

Pecans can dramatically reduce bad cholesterol and fat levels

by Study Finds

ATHENS, Ga. — Adding more pecans to your diet can dramatically improve cholesterol and fat levels, leading to better heart health, a new study finds.

Researchers from the University of Georgia find people at risk for heart disease who ate pecans during an eight-week trial displayed “significant” improvements in total cholesterol, low-density lipoprotein (LDL) or “bad” cholesterol, and triglycerides — which are fats the body stores in cells.

The team saw an average drop of five percent in total cholesterol and between six and nine percent in LDL among participants who ate the nuts as part of their daily diet.

“This dietary intervention, when put in the context of different intervention studies, was extremely successful,” says study co-author Professor Jamie Cooper in a university release. “We had some people who actually went from having high cholesterol at the start of the study to no longer being in that category after the intervention.”

The research team finds these nuts beat out 51 exercise plans designed to lower cholesterol, which reported an average drop of one percent in total cholesterol and five percent in LDL cholesterol.

“The addition of pecans to the diet not only produced a greater and more consistent reduction in total cholesterol and LDL compared to many other lifestyle interventions, but may also be a more sustainable approach for long-term health,” Dr. Cooper adds. “Some research shows that even a 1% reduction in LDL is associated with a small reduction of coronary artery disease risk, so these reductions are definitely clinically meaningful.”

Adding pecans (any way you can) improves health

For the study, researchers assigned 52 adults between the ages of 30 and 75 who were at higher risk for cardiovascular disease to one of three groups. One group consumed 68 grams (about 470 calories) of pecans a day as part of their regular diet. The second group did not add the nuts on top of their normal diet, but replaced other things they ate with the same number of calories in pecans. The third control group did not eat any pecans at all.

At the eight-week mark, participants ate a high-fat meal which allowed researchers to detect changes in the fats and sugars in their blood. Results revealed improvements in the levels of fat in blood among the two pecan groups, while post-meal triglycerides dropped in the group that added pecans. Blood sugar levels were also lower in the group that replaced parts of their usual diet with pecans.

“Whether people added them or substituted other foods in the diet for them, we still saw improvements and pretty similar responses in total cholesterol and LDL cholesterol in particular,” Dr. Cooper explains.

The team says their findings back up previous research which revealed bioactive properties of pecans for possible mechanisms driving the improvements. They added that pecans are high in healthy fatty acids and fiber, both of which contribute to lower cholesterol.

The findings appear in The Journal of Nutrition.

South West News Service writer William Janes contributed to this report.

Good News Monday: The Upside of Bad Cholesterol

Not that this is license to eat vast quantities of Brie, but it’s reassuring to know that if you take medicine for cholesterol management one surprising benefit is that it also seems to reduce COVID severity.

In a new study, researchers found that patients taking statin medications had a 41% lower risk of in-hospital death from COVID-19. Confirming their earlier hypothesis, statins have anti-inflammatory effects and binding capabilities, which could explain how they stop progression of the virus.

Photo by cottonbro on Pexels.com

Good News Monday: A New Way to Heal a Broken Heart

Another fascinating story from StudyFinds.com

broken heart woman
(Credit: RODNAE Productions from Pexels)

Researchers discover drug that can mend the physical damage of a broken heart

by Chris Melore

MELBOURNE, Australia — From someone experiencing chest pain after a breakup, to a married couple dying within minutes of each other, there are many real examples of what doctors call broken heart syndrome. While the emotional scars are a separate issue, there may finally be a way to prevent lasting physical injury. Researchers in Australia say, for the first time, scientists have uncovered a drug that can literally mend a broken heart.

A team from Monash University find Suberanilohydroxamic acid (SAHA) can significantly improve cardiac health due to this condition. In their study, researchers used SAHA to target genes affected by a “broken heart” — or Takotsubo cardiomyopathy.

Although many may think broken heart syndrome is just a saying, doctors know it to be a very real ailment. Patients suffer a weakening of the left ventricle, the heart’s main pumping chamber. Stressful emotional triggers, usually following a traumatic event like the death of a loved one, often cause this problem. Researchers add broken heart syndrome can mimic a heart attack, causing chest pain, shortness of breath, and an irregular heartbeat.

How does SAHA heal the heart?

Suberanilohydroxamic acid is currently serving as a cancer treatment, with the U.S. Food and Drug Administration approving its use. The drug works on the heart by protecting certain genes and the acetylation/deacetylation (Ac/Dc) index in particular. This is a vitally important process which regulates gene expression in humans.

“We show for the first time a drug that shows preventative and therapeutic benefit is important to a healthy heart. The drug not only slows cardiac injury, but also reverses, the damage caused to the stressed heart,” says study leader Professor Sam El-Osta from Monash Central Clinical School in a university release.

Mostly women suffer from this mysterious condition

The study finds, in western nations, broken heart syndrome almost exclusively affects women, especially after menopause. In fact, researchers say up to eight percent of women believed to be having a heart attack may actually be dealing with Takotsubo cardiomyopathy.

While the symptoms are similar, the exact cause of the physical pain of a broken heart is still a mystery. Doctors believe a surge of stress hormones flood the heart during a traumatic event. This may cause changes in the heart muscles and blood vessels which prevent the left ventricle from working properly. The result is the heavy, achy feeling people get in the chest that can be mistaken for a heart attack.

The good news is most people recover from broken heart syndrome within two months. The bad news, unfortunately, is that some patients may suffer from heart failure due to their extreme trauma. Although death from a broken heart is rare, researchers say 20 percent of patients experience some degree of heart failure. Until now, there has been no standard treatment to alleviate this condition.

“This pre-clinical study describes a new standard in preventative and therapeutic potential using a cardioprotective drug that targets genes in the heart,” Professor El-Osta concludes.

“The team is committed to the research of women’s health recognizing the uneven sex prevalence of almost 9:1 (female to male). Based on these promising results we are focused on the continued development of compounds like SAHA to improve cardiac benefit and healthier life.”

The study appears in the journal Signal Transduction and Targeted Therapy.

Good News Monday: Statins, stat!

For us older folks with cholesterol concerns — mine’s hereditary; thanks, Dad — today’s NY Times article had some heartening info.

For Older People, Reassuring News in the Statin Debate

There is accumulating evidence that the benefits of statins far outweigh possible risks, and nearly all statins on the market are now available as inexpensive generics.

Credit…Gracia Lam
Jane E. Brody

By Jane E. Brody

  • Sept. 21, 2020, 5:00 a.m. ET

Cholesterol-lowering statin drugs, already one of the most popular medications worldwide, may become even more widely used as evidence grows of their safety and value to the elderly and their potential benefits beyond the heart and blood vessels.

Among the latest are reports of the ability of several leading statins to reduce deaths from common cancers and blunt the decline of memory with age. Perhaps such reports will persuade a reluctant 65-year-old friend who has diabetes, and others like him, that taking the statin his doctor strongly advised is a smart choice.

In addition to accumulating evidence that the benefits of statins far outweigh possible risks for the vast majority of people for whom they are now recommended, nearly all statins on the market are now available as inexpensive generics.

Full disclosure: I have a strong family history of heart disease and have been taking a statin — atorvastatin, originally marketed as Lipitor — for many years after dietary changes failed to control a steadily rising blood level of artery-damaging LDL-cholesterol. My prescription is now fully covered by my Medicare Part D insurance with no co-pay.

But cost of a medication is not the only consideration for a drug that can be lifesaving for many people. The primary indication for taking a statin is to reduce the risk of a heart attack or stroke by lowering serum LDL-cholesterol and, in some cases, also triglycerides, both of which can damage coronary arteries when levels rise above normal.

Statins offer further cardiovascular protection by stabilizing the fatty deposits in arteries called plaque that can break loose, block a major artery and cause a heart attack or stroke.

Current guidelines typically recommend statin therapy for:

  • People with a history of heart disease, stroke or peripheral artery disease or risk factors that give them a 10 percent or greater chance of a heart attack within 10 years;
  • People over 40 with diabetes and an LDL-cholesterol level above 70 milligrams per deciliter;
  • People over 21 with an LDL-cholesterol level of 190 or higher (despite dietary changes to minimize saturated fats and achieve a normal body weight).

Currently, more than 60 percent of older people in the United States who, like me, have high cholesterol take a statin to help prevent a heart attack or stroke.

Still, there’s been a long-simmering debate as to whether statins are advisable for people over 75, even though the risk of suffering life-threatening cardiovascular disease rises precipitously with age. Concerns have been raised about side effects associated with statins, potential adverse effects of the drugs on other ailments common in the elderly and possible harmful interactions with the many other medications they often take.

Writing in the Harvard Health Blog last October, Dr. Dara K. Lee Lewis noted, “The paradox that we face is that as our patients age, they are at increased risk for heart attacks and strokes, and yet they also become more sensitive to medication side effects, so it is a tricky balance.”

Statins can sometimes cause blood sugar abnormalities, resulting in a diagnosis of pre-diabetes or diabetes, and possible toxic effects on the liver that necessitate periodic blood tests for liver enzymes. A very small percentage of people prescribed a statin develop debilitating muscle pain. An elderly friend developed statin-induced nightmares. There have also been reports suggesting statin-associated memory problems and cognitive decline, already a common concern as people age.

But likely the biggest deterrent was the existence of meager evidence for the role statins might play for older people at risk of cardiovascular disease. As is true in most drug trials on new medications, relatively few people over 75 were included in early studies that assessed the benefits and risks of statins.

The latest reports, however, are highly reassuring. One followed more than 120,000 French men and women ages 75 to 79 who had been taking statins for up to four years. Among the 10 percent who stopped taking the drug, the risk of being admitted to a hospital for a cardiovascular event was 25 to 30 percent greater than for those who continued taking a statin.

Another study in Israel, published last year in the Journal of the American Geriatrics Society, involved nearly 20,000 older adults followed for 10 years. Among those who stayed on statin therapy, the chance of dying from any cause was 34 percent lower than among those who failed to adhere to a prescribed statin. The benefits were not reduced for those older than 75 and applied to women and men alike.

This year a study published in JAMA by a team headed by Dr. Ariela R. Orkaby of the VA Boston Healthcare System found that among 326,981 United States veterans whose average age was 81, the initiation of statin use was associated with 25 percent fewer deaths over all and 20 percent fewer cardiovascular deaths during a follow-up of nearly seven years.

However, none of these studies represent “gold standard” research. The results of two such studies, the Staree trial and the Preventable trial, both randomized controlled clinical trials of statin therapy to prevent cardiovascular events in the elderly, have not yet been published. Both will also assess effects on cognition.

Meanwhile, a report last year from Australia published in the Journal of the American College of Cardiology found no difference over a six-year period in the rate of decline in memory or cognitive status between statin users and those who had never taken the drugs. In fact, among those who started a statin during the study, the rate of memory decline was blunted. Another observational study by a Swedish team published in Nature found beneficial effects on reaction time and fluid intelligence among statin takers over 65.

Finally, there are several reports that a major class of statins called lipophilic (including atorvastatin, simvastatin, lovastatin and fluvastatin) may have anticancer effects. One study of nearly 2,000 survivors of early-stage breast cancer found a decreased five-year recurrence rate in women who started a statin within three years of diagnosis.

In a report presented in June to a virtual meeting of the American Association for Cancer Research, Dr. Kala Visvanathan of Johns Hopkins Medicine in Baltimore described a 40 percent reduction in deaths from ovarian cancer among more than 10,000 patients who had used statins either before or after their diagnosis. The patients who benefited in this observational study had the most common and aggressive form of ovarian cancer.

Dr. Visvanathan explained that statins inhibit an enzyme in a chemical pathway involved in the growth and proliferation of tumors. At a press briefing, Dr. Antoni Ribas, president of the association, said that if the finding is confirmed in a randomized clinical trial, “this would be a great outcome.”

Good News Monday: Even One Exercise Session Has Benefits

color colour fitness health

Photo by Pixabay on Pexels.com

A single exercise session that ups your heart rate can lower blood pressure, improve sleep, reduce anxiety and improve insulin sensitivity on the day you do it.

The big benefits such as lowering your risk of many chronic diseases and cancers start adding up within days or weeks of starting regular physical activity.  The current guidelines are:

  • Move more, sit less. Some physical activity is better than none.
  • Spread aerobic activity through the week. Aim for at least 2.5 -5 hours of moderate intensity or 1.25 – 2.5 hours of vigorous intensity.
  • Strength train at least twice a week. Your bones, joints and muscles need love!
  • Add balance training as you get older.  Yoga, tai chi and other activities help prevent falls.
  • Anyone with chronic conditions should be as physically active as
    their abilities and conditions allow.
  • Pregnant? Stay moderately active, per your doctor’s advice.

What’s moderate vs. what’s vigorous? Per the guidelines, moderate activity means you’re breathing hard and can hold a conversation, but you can’t sing. (OK, some of us can’t sing no matter what.) “Vigorous” means you can’t get more than a couple of words out without a breath.

Exercise with others and live longer! A recent Mayo Clinic study of more than 8500 participants found that playing team and partner sports added years to their lives vs exercising alone:

  • Tennis: +9.7 yrs
  • Badminton +6.2 yrs  (I am not making this up)
  • Soccer +4.7 yrs
  • Jogging +3.2 yrs
  • Gym +1.5 yrs
  • Group exercise classes or clubs also boost longevity

panoramic view of people in bicycles

Photo by Pixabay on Pexels.com

Good News Friday: Health Benefits of Drinking Beer

TGIF! I had a crazy week and couldn’t manage a post on Monday, but this news should make up for it.

Cheers, and have a “hoppy” weekend!

alcohol alcoholic background bar

Photo by Pixabay on Pexels.com

Good News Monday: Cat Owners Live Longer

A University of Minnesota study conducted over a 10-year period found that cat owners lowered their risk of heart attack by nearly 30%. Meowza!

Other research supports these findings, and lists even more benefits:

  1. Reduced risk of heart disease is similar to going on a low-salt diet
  2. Boosts your immune system
  3. Helps children avoid developing allergies
  4. Lowers blood pressure
  5. Lowers cholesterol and triglyceride levels
  6. Reduces the risk of stroke
  7. Heals bones and muscles
  8. Reduces stress and anxiety
  9. Improves mood
  10. Lessens feelings of loneliness and depression

Here’s the full article I found, complete with adorable photos.

kitten cat rush lucky cat

Photo by Pixabay on Pexels.com

Good News Monday? Eggs-actly!

I have high-ish cholesterol (controlled by medication); as a result, I tend to avoid eating eggs. But a little research has revealed that they’re more good than bad for our health.

While it’s true that chicken eggs are high in cholesterol, their effect on blood cholesterol is minimal when compared with the effect of trans fats and saturated fats; i.e., skip the bacon/ham/sausage/frying in butter part. Instead, opt for poached eggs or make your omelet with one egg white + one whole egg and cook it in olive oil.

According to experts, most healthy people can eat up to seven eggs a week with no increase in their risk of heart disease, and some scientists don’t see a problem with eating as many as three a day. (The main problem would probably be how boring that would be!)

Eggs consistently raise HDL (“healthy”) cholesterol. For 70% of people, there is no increase in total or LDL (“lousy”) cholesterol, though some people may experience a mild increase in a benign subtype of LDL.

As a good source of inexpensive, low-calorie, high quality protein, eggs are hard to beat (pun intended). More than half their protein is found in the egg white, along with vitamin B2 and lower amounts of fat than the yolk.

Along with beneficial fat, they also contain biotin and vitamin B12 (great for skin, hair and nails), plus vitamin A and lutein, which support eye health. Some stats:

  • Vitamin A: 6% of the RDA.
  • Folate: 5% of the RDA.
  • Vitamin B5: 7% of the RDA.
  • Vitamin B12: 9% of the RDA.
  • Vitamin B2: 15% of the RDA.
  • Phosphorus: 9% of the RDA.
  • Selenium: 22% of the RDA.
  • Eggs also contain decent amounts of vitamin D, vitamin E, vitamin K, vitamin B6, calcium, and minerals such as iron, copper and zinc (which supports a healthy immune system).
  • Virtually all egg yolks contain omega-3 fats. And of course, egg whites contain no cholesterol.

I’m pretty sure there are health benefits associated with an accompanying mimosa, too, aren’t you?!

beverage breakfast drink orange juice

Photo by JÉSHOOTS on Pexels.com