Tag Archives: prevention

Good News Monday: Bone Up on Calcium


Taking calcium supplements before age 35 may prevent osteoporosis later in life
[John Anderer, studyfinds.com]

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Planning ahead can pay serious dividends in many areas of life. Now, new research out of China suggests a little bit of forward thinking when it comes to bone health can help stave off osteoporosis years down the line. Researchers report taking calcium supplements between ages 20 and 35 can help improve bone mass at peak bone mass age.

Study authors believe this work points to a new, easy way adults can proactively protect their bones from a young age, setting the stage for more robust bone health during old age. On an even more general level, researchers add young adults should pay more attention to their bone health.

“Osteoporosis and fractures are important global public health problems, particularly in elderly women,” explains lead study author Yupeng Liu, a researcher at Wenzhou Medical University’s School of Public Health and Management, in a media release. “However, although calcium supplementation has been widely used in older age to increase bone mass, a number of studies suggest that it is unlikely to translate into clinically meaningful reductions in fractures.”

“On the other hand, intervention before young adults reach peak bone density might have a greater impact on bone health and prevent osteoporosis later. There has been considerable debate about whether calcium supplementation has effects on bone health among young people, so we conducted a comprehensive review of the evidence for calcium supplement effectiveness in people under the age of 35.”

Are supplements better than the real thing?
The research team made use of previously conducted randomized controlled trials — seen as the gold standard for clinical research — to compile these findings. More specifically, they searched for trials comparing calcium or calcium plus vitamin D with a placebo or no treatment in participants under the age of 35. They also focused on results reported for bone mineral density (BMD) or bone mineral content (BMC).

In total, this project ended up encompassing 43 prior studies involving over 7,300 people. Among those 43 studies, 20 looked at dietary calcium while the other 23 focused on calcium supplementation. The team then combined all of the data to search for changes in BMD and BMC in the lumbar spine, femoral neck, total hip, and total body.

That investigation led to the conclusion that calcium supplements taken by people under 35 have significant potential to improve the BMD levels of both the total body and femoral neck. They also appear to slightly increase the BMC of the femoral neck, total body, and lumbar spine. In comparison to individuals younger than 20 (the pre–peak bone mass age), these benefits were more prominent among participants between 20 and 35 years-old (the peri–peak bone mass age when bone mass plateaus).

Importantly, both dietary sources of calcium and calcium supplements had a positive effect on femoral neck and total body BMD. However, BMC measurements of the femoral neck and lumbar spine only improved following calcium supplementation.

Vitamin D, meanwhile, was a bit of a mixed bag. A combination of calcium and vitamin D did prove more beneficial for the femoral neck bone mineral density and content, but researchers did not see the same robust benefits for BMCs of lumbar spine and total body, or total body BMD.

Moving up the ‘intervention window’
In summation, study authors believe calcium supplements have serious potential to improve both bone mineral density and content, especially in the neck, in a major way. Taking calcium supplements during peri–peak bone mass age (ages 20-35) appears to foster the strongest benefits in comparison to earlier or later in life.

“Although further trials will be needed to verify these findings, our review provides a new train of thought regarding calcium supplementation and the optimal timing of its effects,” concludes senior study author Shuran Wang, a professor at Wenzhou Medical University. “In terms of bone health and an individual’s full life cycle, the intervention window of calcium supplementation should be advanced to the age around the plateau of peak bone mass – namely at 20–35 years of age.”

The study appears in the journal eLife.

Good News Monday: A Cancer Vaccine?

BERLIN (AP) — The scientist who won the race to deliver the first widely used coronavirus vaccine says people can rest assured the shots are safe, and the technology behind it will soon be used to fight another global scourge — cancer.

Ozlem Tureci, who co-founded the German company BioNTech with her husband, was working on a way to harness the body’s immune system to tackle tumors when they learned last year of an unknown virus infecting people in China.

Over breakfast, the couple decided to apply the technology they’d been researching for two decades to the new threat, dubbing the effort “Project Lightspeed.”

Within 11 months, Britain had authorized the use of the mRNA vaccine BioNTech developed with U.S. pharmaceutical giant Pfizer, followed a week later by the United States. Tens of millions of people worldwide have received the shot since December.

“It pays off to make bold decisions and to trust that if you have an extraordinary team, you will be able to solve any problem and obstacle which comes your way in real time,” Tureci told The Associated Press in an interview.

Among the biggest challenges for the small, Mainz-based company that had yet to get a product to market was how to conduct large-scale clinical trials across different regions and how to scale up the manufacturing process to meet global demand.

Along with Pfizer, the company enlisted the help of Fosun Pharma in China “to get assets, capabilities and geographical footprint on board, which we did not have,” Tureci said.

Among the lessons she and her husband, BioNTech chief executive Ugur Sahin, learned along with their colleagues was “how important cooperation and collaboration is internationally.”

Tureci, who was born in Germany to Turkish immigrants, said the company, which has staff members from 60 countries, reached out to medical oversight bodies from the start, to ensure that the new type of vaccine would pass the rigorous scrutiny of regulators.

“The process of getting a medicine or a vaccine approved is one where many questions are asked, many experts are involved and there is external peer review of all the data and scientific discourse,” she said.

Amid a scare in Europe this week over the coronavirus shot made by British-Swedish rival AstraZeneca, Tureci dismissed the idea that any corners were cut by those racing to develop a vaccine.

“There is a very rigid process in place and the process does not stop after a vaccine has been approved,” she said. “It is, in fact, continuing now all around the world, where regulators have used reporting systems to screen and to assess any observations made with our or other vaccines.”

Tureci and her colleagues have all received the BioNTech vaccine themselves, she told the AP. “Yes, we have been vaccinated,” she said.

As BioNTech’s profile has grown during the pandemic, so has its value, providing funds the company can use to pursue its original goal of developing a new tool against cancer.

The vaccines made by BioNTech-Pfizer and U.S. rival Moderna uses messenger RNA, or mRNA, to carry instructions into the human body for making proteins that prime it to attack a specific virus. The same principle can be applied to get the immune system to take on tumors.

“We have several different cancer vaccines based on mRNA,” said Tureci, who is BioNTech’s chief medical officer.

Asked when such a therapy might be available, Tureci said “that’s very difficult to predict in innovative development. But we expect that within only a couple of years, we will also have our vaccines (against) cancer at a place where we can offer them to people.”

For now, Tureci and Sahin are trying to ensure the vaccines governments have ordered are delivered and that the shots respond effectively to any new mutation in the virus.

On Friday, German President Frank-Walter Steinmeier awarded the wife and husband one of the country’s highest decorations, the Order of Merit, during a ceremony attended by Chancellor Angela Merkel, a trained scientist herself.

“You began with a drug to treat cancer in a single individual,” Steinmeier told the couple. “And today we have a vaccine for all of humanity.”

Tureci said ahead of the ceremony that getting the award was “indeed an honor.”

But she insisted developing the vaccine was the work of many.

“It’s about the effort of many: our team at BioNTech, all the partners who were involved, also governments, regulatory authorities, which worked together with a sense of urgency,” Tureci said. “The way we see it, this is an acknowledgement of this effort and also a celebration of science.”

An Ounce of Prevention

A friend passed along a medical professional’s advice that seems to be echoed by other sources. Couldn’t hurt and makes sense.

Introduction: The Chinese now understand the behavior of COVID-9, after analysis of multiple autopsies.  The virus obstructs respiratory pathways with thick mucus that solidifies and blocks the airways and lungs.

To apply medicine, you have to open and unblock the airways so treatment can be used, which takes several days.

RECOMMENDATIONS TO SAFEGUARD YOURSELF

  1. Drink lots of HOT LIQUIDS such as coffee, soup, tea and hot water.  Also, sip WARM water every 20 minutes because this keeps your mouth moist and washes any virus into the stomach, where gastric juices will neutralize it before it gets to the lungs.
  2. Once a day, GARGLE with an antiseptic in warm waer, such as lemon juice, vinegar or salt.
  3. The virus ATTACHES to clothes and hair.  Any soap or detergent kills it.  SHOWER or bathe IMMEDIATELY when you get in from the street.  Avoid sitting and go straight to the shower.  If you can’t wash your clothes daily, hang them in direct SUNLIGHT, which also neutralizes the virus.
  4. Clean METALLIC SURFACES especially carefully, because the virus can remain viable on these surfaces up to 9 days.  Be extra vigilant about cleaning hand rails, door handles etc., and regularly wipe down these surfaces at home.
  5. DON’T SMOKE!
  6. WASH HANDS every 20 minutes for 20 seconds with any soap that FOAMS.
  7. Eat plenty of fruits and vegetables.  Try to elevate your ZINC levels, not just VITAMIN C. Meat, shellfish, legumes, nuts and eggs are a few food sources.
  8. Animals do not spread the virus. It is passed on by PERSON TO PERSON contact.
  9. Try to AVOID catching the common flu, which will weaken your immune system, and also avoid cold foods and beverages.
  10. If you feel ANY DISCOMFORT in your throat, or a SORE THROAT coming on, attack it immediately using the above methods.  The virus ENTERS THIS WAY and remains 3-4 days before it passes into the lungs.

Best of luck to us all, and please don’t go out unless it’s absolutely necessary.  xx Alisa

The Ick Factor

Something new to worry about — with an easy fix.

According to a microbiologist, we should be washing all our towels after three uses, max.  That’s because damp towels are breeding grounds for bacteria, which we’ll then transfer to our bodies. Yuck, right?

The solution: sniff your towel. If it stays damp too long it will develop an odor, which is your cue to wash it, pronto.

bathroom bathtub ceramic clean

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